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Zepbound (Tirzepatide) Results Average Weight Loss: In major clinical trials (such as the SURMOUNT-1 trial), participants taking the highest dose of Zepbound lost an average of 20.9% of their body weight over 72 weeks

Besides, circulating TMAO levels are associated with NASH mainly in the presence of type 2 diabetes (Leon-Mimila et al., 2021)

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Counselling is necessary at different stages of the disease onset, including during diagnosis, adolescence, transfusion, before and after genetic testing, prior to pregnancy, and during regular follow-ups to reinforce patient education