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[12] The oral upper intake levels established for dietary copper do not translate directly to a copper-carrying peptide delivered subcutaneously, which bypasses the intestinal regulation of copper absorption entirely one more reason the systemic dosing of GHK-Cu is genuinely uncharacterized in humans

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Drug Treatment In this study, we used FOXO4 D-Retro-Inverso peptide (FOXO4-DRI, NovoPro, Shanghai, China) and ABT-263 (Apexbio Technology, Houston, TX, United States) to selectively remove the senescent chondrocytes

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