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The patient had previously been treated with tirzepatide but reportedly achieved only moderate weight loss, and Muniyappa advised against bariatric surgery given the patient's age and comorbidities

The curve climbs faster because you are adding a larger dose on top of an already-established baseline

There is no MHRA-approved indication for GLP-1 receptor agonists in Hashimoto's thyroiditis, and any such use would be off-label

But in recent years, many women with Lipedema have began using GLP-1s for different reasons: to help manage inflammation, pain, swelling, and mobility