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Ding L, Zhang F, Zhao M-X, Ren X-S, Chen Q, Li Y-H et al (2016) Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity

Conclusions In this clinically relevant model of septic shock, the addition of PCZ to the standard resuscitation regimen alleviated the hemodynamic alterations, resulting in reduced catecholamines requirements and a lower fluid balance to maintain adequate tissue perfusion