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In their study, Yong et al

Moreover, there were consistently larger proportions of patients covered by treatment than there were patients who had not discontinued treatment (estimated as 1 minus the cumulative incidence of treatment discontinuation) for both study drugs, with these differences increasing over the follow-up period

Furthermore, to evaluate the blockade of autophagic flux by PFOS, lysosomal inhibitor chloroquine (CQ) was added to PFOS-treated RTCs during the final hour of the 4-h PFOS treatment