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This is the second messenger system that leads to PKC activation and calcium mobilization

Overall, high concentrations of reactive species produced by immune response, oxidative metabolism, and other environmental factors create a complex landscape of oxidative stress that the parasite has to deal with to maintain redox homeostasis for its survival in diverse hosts

GSH Nebraska: general info + transporters Comprehensive reviews The Incomplete Glutathione Puzzle: Just Guessing at Numbers and Figures?2017 Tissue distribution and concentration 2-5 mM according to the tissue (5 mM = 1,5366 mg/ml) half-life GSH half life It ranges from 3/5 hours to 30/50 hours If we assume 40kg tissues with an average 2.5 mM GSH (ca 750 mg/l) it means 30 g GSH in the whole body with an half-life of 48hours its life is around 10 days

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