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A comparison of copper binding properties, copper exchange rate and redox potential between two similar naturally occurring copper-binding peptides GHK and DAHK shows that even though both bind copper in stoichiometry at a ratio of 1:1, the exchange rate of copper between DAHK peptides is very slow, while the exchange rate between GHK peptides is much faster
doi: 10.3389/fphar.2022.1026182 Received 23 August 2022 Accepted 23 November 2022 Published 14 December 2022 Volume 13 - 2022 Edited by Junmin Zhang, Lanzhou University, China Reviewed by Yurong Lai, Gilead, United States Mei-Hua Qu, Weifang Second Peoples Hospital, China Updates Copyright 2022 He, Feng, Guo, Zhou, Li, Zhang, Zhang, Wang, Wang, Hao, Zhang, Gao, Gu, Zhang, Li and Li
Protein kinase C type isoform 2 (PKCII) is able to recognize the initial lipid peroxidation, promote the phosphorylation of ACSL4 on Thr328 to activate phospho-ACSL4, and facilitate the incorporation of PUFA into PLs, leading to the termination of the cells (9)
