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3.2.3 Phylum Proteobacteria As a key component of the gut microbiome predominantly composed of Gram-negative bacteria, increased Proteobacteria abundance is closely associated with epithelial barrier dysfunction and elevated intestinal permeability (Heckmann et al., 2025)

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The results demonstrated that citicoline significantly limited cognitive impairments in the domains of attention and executive functions and temporal orientation at 6 and 12 months post-stroke in treated compared to untreated patients (97)