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Methods We conducted a systematic review of prospective studies reporting T with and without GLP-1 RA treatment

Conversely, amylin also appears to have gastric-emptying-independent effects on islet alpha cells, so the two are not perfectly yoked

The findings point to a broader cardiometabolic and anti-inflammatory effect from the increasingly popular class of medications, which are commonly prescribed for diabetes, obesity and heart failure

Limitations and future directions As with any animal study, the limitation of the current study is the application of its findings to human settings, which is challenging due to both obvious and subtle distinctions between humans and animals