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[3] In REDEFINE 2 , a parallel 68-week Phase 3a trial in 1,206 adults who had overweight or obesity and type 2 diabetes, once-weekly CagriSema produced an estimated mean weight change of 13.7% versus 3.4% with placebo, alongside marked improvements in glycemic control

The peptides are beginning to interact with pineal cells and neural circuits, but the biological response takes time to manifest

Doctors may also try phototherapy, which stimulates cells to make skin pigment, but this option is not always easy to implement as it can be expensive and involves going into an office equipped with phototherapy devices multiple times a week, every week