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In MS patients, administering a mixture of probiotics (enriched with Lactobacillus, Streptococcus , and Bifidobacterium ) switched the peripheral immune response to an anti-inflammatory one and reversed the microbiota composition changes associated with MS (Lavasani et al., 2010)

Moreover, since this function was inherited from engulfed prokaryotes which became mitochondria, the melatonin synthesizing capacity was presumably retained in these organelles to the present day

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In addition, it was found that DSIP treatment may be beneficial for patients dependent on pain medications because it reduces detox symptoms