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When taking melatonin or any new supplement, some people may be more at risk, including: People with an existing heart failure diagnosis Adults older than 65, as age often brings additional health concerns and a higher likelihood of taking multiple medications Individuals with multiple risk factors for heart disease, such as: People in these groups may not only be taking melatonin, but also other supplements or prescription medications

Being morbidly overweight can increase other potentially life-threatening healthcare risks prompting much concern in the medical community