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25 As development progresses, MKs form polyploids through endomitosis and are regulated by the SHP1/SHP2 and G6b-B, a receptor containing the immunoreceptor tyrosine-based inhibition motif (ITIM)

Investigating the effects of GLP-1 receptor agonists on thyroid autoimmunity

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Overall, existing inhibitors suffer from insufficient selectivity, highlighting the urgent need for LONP1-specific agents developed through advanced approaches such as cryo-electron microscopy and molecular dynamics simulations to expand therapeutic options