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Pathologic fusion of the Ewing gene EWS to WT1 (t(11;22)(p13;q12)( EWS/WT1 )) has been shown to abrogate the tumour suppressor function of WT1 and to generate an oncogenic chimeric protein capable of binding and activating the IGF-1R promoter (Karnieli et al, 1996)

while there is no evidence of harm at that level, caution is advised

& Forloni, G

Here's what he said: $HIMS THE FDA PEPTIDES VOTE IS DAYS AWAY Peptides insider @DrJesseMorse expects approval We discuss the FDA briefing document recommending *against* the 7 peptides, what the odds of approval are for each of the peptides under review (including BPC-157) and why U.S.-made