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Concomitantly, sulforaphane significantly reduced the nuclear translocation of the pro-inflammatory transcription factor nuclear factor (NF)-B in pancreatic acinar cells, downregulating the expression of NF-B target genes that code for pro-inflammatory mediators, such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and IL-6 ( Figure 3 ) (18)

Mechanisms underlying the phytotoxicity and genotoxicity of aluminum and their alleviation strategies: a review

The peptide works best as part of a comprehensive approach including proper nutrition, regular exercise, and lifestyle optimization rather than as a standalone intervention