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The treatment difference in weight analysis was limited to 35 studies and overall, results suggested that semaglutide tablets were more efficacious for treatment differences in weight versus the majority of other second-line treatments

Contraindications include personal or family history of medullary thyroid cancer or MEN2 syndrome, a history of pancreatitis, and severe kidney or liver disease

Do not take two doses at the same time to make up for a missed dose