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Description

Thus, SARS-CoV-2-mediated cell surface reduction of hACE2 receptors could trigger widespread inflammatory sequelae observed in COVID-19, which may linger through long-COVID for an extended period of time

10.1006/bbrc.1997.6943 63 ItohK.WakabayashiN.KatohY.IshiiT.IgarashiK.EngelJ

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 90% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof