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These proteins exert numerous functions such as serving as intracellular Ca 2+ sensors, transduction of Ca 2+ signaling, response to extracellular stimuli, energy metabolism, and regulating cell proliferation and apoptosis

The preparation must be inserted strictly during the final phase of the formulation (cooling phase), at temperatures below 40C

This suggests that direct inhibition of Keap1-Nrf2 PPI might be beneficial for UC treatment

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