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Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

11 It was later determined that higher concentrations were necessary to produce the same effect in vivo

In the technical scheme of the invention, the coupling of the ionic liquid Linker to the solid-phase resin comprises the following steps: step one, reacting 1- (2-hydroxyethyl) imidazole or 1- (3-hydroxypropyl) -1H-imidazole with isobutene, extracting and crystallizing to obtain tert-butyl protected 1- (2-hydroxyethyl) imidazole or 1- (3-hydroxypropyl) -1H-imidazole

Lee, PharmD, MAS, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Dr, Mail Code 0719, Pharmaceutical Sciences Bldg, La Jolla, CA 92093 ([email protected])