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Wettergren A, Wojdemann M, Meisner S, Stadil F, Holst JJ

406 Therefore, endogenous GLP-1R signaling in astrocytes plays a critical role in maintaining mitochondrial homeostasis and is dependent on FGF21 to effectively regulate glucose metabolism

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In England, these are typically structured as Tier 3 (specialist multidisciplinary services) or Tier 4 (bariatric surgery services), with referral criteria that may vary by Integrated Care System (ICS)