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e , Mitochondria/nuclear DNA ratio in gWAT from control and NDI1 mice at 3 months of age (n = 6 Control and 5 NDI1)

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Side effects of Januvia Headache Upper respiratory symptoms (sore throat, runny/stuffy nose) Sore throat Hypoglycemia (when combined with insulin or sulfonylureas) Heart failure (fatigue, dyspnea, edema, sudden weight gain) Pancreatitis (persistent nausea/vomiting, severe abdominal pain) Allergic reactions (hives, facial swelling, anaphylaxis) Kidney problems (decreased function or dialysis) Severe skin reactions (StevensJohnson syndrome, blisters) Severe joint pain Side effects of metformin Diarrhea Nausea/vomiting Indigestion and gas Headache Stomach pain Lactic acidosis (rare

This is the first new medication approved since 2014 as an addition to diet and physical activity indicated for adults with obesity (initial BMI 30 kg/m2) or overweight (initial BMI 27 kg/m2) with at least one weight-related medical condition