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If you have cardiovascular risk factors such as high blood pressure, high cholesterol, or a history of heart disease, your healthcare provider may consider GLP-1 shots as part of your treatment plan to help reduce your risk of cardiovascular complications

Animal studies showed retatrutide producing lower expression levels of inflammatory and fibrotic mediators compared to tirzepatide, suggesting the triple mechanism may offer benefits beyond additional weight loss

XIGDUO XR is not indicated for glycemic control in patients with type 1 diabetes mellitus

This guide breaks down every meaningful difference between retatrutide and semaglutide