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In contrast, female Gpr146 / mice showed robust activation of classical thermogenic program

Distinct alterations of hypothalamic proteomic profiles by GLP1/E in lean and obese PCOS mice Finally, considering that the hypothalamus is likely the primary target of the GLP1/E conjugate, we assessed changes in global hypothalamic proteome in PWA and PNA mice following GLP1/E treatment, using cutting-edge liquid chromatographytandem mass spectrometry (LC-MS/MS)

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As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, it helps people manage their blood sugar levels