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This dual effect is relevant in weight management, as blood sugar fluctuations can impact hunger and energy balance

UC Davis exercise physiologist Keith Baar, speaking in late 2025, put it plainly: "It is still important for patients taking GLP-1 medication to limit muscle wasting through exercise and high-quality protein." The American College of Sports Medicine and major endocrinology bodies now recommend that GLP-1 users prioritize: Resistance training with multijoint movements - exercises that load multiple muscle groups simultaneously and create high mechanical tension, particularly in the posterior chain (glutes, hamstrings, lower back) Progressive overload - progressively increasing the demand on the muscles over time to continue signaling retention and growth Consistent training frequency - 3 to 5 sessions per week to maintain the anabolic signal during prolonged caloric restriction Adequate protein intake - 1.2 to 2.0 grams per kilogram of body weight daily, timed around training sessions The challenge for most GLP-1 users is practical: they're often new to structured training, may have limited mobility or joint issues related to their previous weight, and don't want to split their routine across a separate cardio machine and a weights area

They found that dosages of 5, 10, and 15 mg resulted in HbA1c reductions ranging from 2.24% to -2.58%

You will learn the new limits of your appetite and to listen to your body when you become full