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Immunology saw strong performances from Skyrizi (up 50.9% to $11.7 billion) and Dupixent (up 22.1%), while Humira declined 37.6% amid biosimilar pressure

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American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 266, R97988

Positive trials are needed before botulin toxin can be recommended for the management of pylorospasm in gastroparesis [5, 12], and the 2013 ACG recommendations on gastroparesis strongly advises against using botox for the treatment this condition [4]