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As such, the AMYR agonists (combined with other incretin class members) could represent the elusive drug candidate to address the multi-hormonal dysregulations of diabetes subtypes and qualify as a precision medicine approach that surpasses the long overdue division into T1DM and T2DM

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This may cause vascular leakage, widened endomysium, and fragmentation of muscle fibers that may be related to edema and accumulation of mucopolysaccharides resulting from necrotic changes (Lind et al., 2021)