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The MTHFR gene (methylenetetrahydrofolate reductase) is responsible for converting folate into its active form, methylfolate

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ZHX2 inhibits YTHDF2 transactivation Based on ChIP-seq data obtained from ENCODE, we observed an enrichment of the transcription factor ZHX2 in the promoter region of the YTHDF2 gene in HepG2 cells (Fig