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and Waters, A.P

Plasma enzyme assay and liver histology Plasma was extracted from whole blood and immediately measured for alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities using a biochemical kit (Diagnostic Chemicals Ltd., Oxford, CT)

John D Hayes, Jack U Flanagan, Ian R Jowsey 2005

The process is dynamic, and involves also the thiolate groups of proteins such as serum albumin and haemoglobin and appears as the main mechanism for the distribution of thiol-binding metals from the absorption site throughout the body and towards the active sites where the toxic action is developed at the molecular level