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"Under-eating, especially long-term calorie restriction, can also slow thyroid function because your body thinks it's in survival mode

In excess, folic acid can: Increase cancer risk [ R ] Raise homocysteine [ R , R , R ] Cause symptoms of folate deficiency [ R , R , R ] Mask anemia caused by low vitamin B12 [ R ] Increase the risk of having children with autism or allergic diseases like asthma and eczema [ R , R ] Possibly increase the risk of having offspring with insulin resistance and high blood lipids (in rats) [ R ] The general recommendation for folic acid intake is 400 micrograms per day or up to 1700 micrograms per day for pregnant women [ R ]

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For instance, Central Asia (0.0, 95% UI: 0.009 to 0.01) exhibited a largely stable burden over the study period