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Regardless of timing, the following general measures may help manage side effects: Eat smaller, more frequent meals rather than large portions Avoid high-fat or spicy foods around the time of injection Stay well hydrated to reduce nausea and support kidney function When to seek urgent medical attention: Contact your GP, trial team, or NHS 111 promptly if you experience severe or persistent abdominal pain (particularly if it radiates to the back), vomiting that prevents you from keeping fluids down, signs of jaundice (yellowing of the skin or eyes), fever, or significantly reduced urine output

These actions may contribute to less irritation of the gut lining, especially in individuals with sensitive digestion

Volatile compounds generated from thermal degradation of alliin and deoxyalliin in an aqueous solution

Microbiome, inflammation and colorectal cancer