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A GHK-Cu eye cream applied for 12 weeks to around-the-eye area of 41 women with mild to advanced photodamage performed better than placebo and vitamin K cream

The J-code for the drug must still accompany it on the claim

the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor

Further linking the relationship between synaptic plasticity and sustained antidepressant effect suggest an important link between this regulatory mechanism and sustained antidepressant effect