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On the other hand, the ACC is thought to process sensory information within emotional and social contexts, regulating affective reactions and forming associations between sensory stimuli and their emotional values [64]

Warfarin: INR may shift as absorption kinetics change with dose escalation

Yukiko Kimura, Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation, PhD Thesis 2010, Department of Paediatric Surgery, Institute of Child Health University College London

Even small changes in metabolism, nutrition, or medication absorption can alter how effectively the therapy works