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Risks and Side Effects of Steroid Use Cardiovascular Risks Steroids can negatively impact heart health by: Raising blood pressure Altering cholesterol levels (lower HDL, higher LDL) Increasing the risk of heart disease and stroke (Thiblin & Petersson, The Lancet Psychiatry , 2005) Hormonal and Reproductive Effects In men, steroid use can cause: Testicular shrinkage Infertility Gynecomastia (male breast tissue development) In women, effects may include: Deepened voice Facial hair growth Menstrual irregularities Both sexes are at risk of acne, liver damage , and hair loss , especially with prolonged or high-dose use

By providing the body with the building blocks it needs to produce glutathione, these precursors can help enhance the absorption and efficacy of glutathione supplements

GLP-1 medications can help lower inflammation and support weight loss, both of which are important in PsA

Nature 405, 635 (2000)