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Even if l-theaninecaffeine combination appears to be inferior to the currently used stimulants, based on our results, there is a potential to use the combination as an adjuvant to increase the number of stimulant-medication free days to prevent tolerance and to complement the action of currently used medications

Immunol Today 1994;15:495-6 62 -Winter BK ea

This loss of collagen and epithelial stiffness is also suggested to be a cause of other diseases and aging-related complications such as corneal 130 , skin 131 and teeth tissue 132 deteroriation