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Azithromycin is one of the safest macrolides, prescribed millions of times in children for ear and throat infections and in adults for respiratory infections

300,301 Recent findings suggest that exposure to certain environmental factors such as pesticides can augment astrocyte proinflammatory signalling and thereby promote CNS autoimmune inflammation

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In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers