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Berberine has nothing to do with GLP-1

Although choices of stroke treatment remain limited, much advance have been achieved in assisting patients in recovering from ischemic stroke, along with progress of recanalization therapy through pharmacological and mechanical thrombolysis

They have an injury secondary to inflammation or something like that

An indirect comparison of data by Novo Nordisk from the STEP 1 trial and the SCALE trial of daily GLP-1 agonist liraglutide suggested 5.81% more weight loss with semaglutide than liraglutide at 68 weeks, and this was backed up by data from the STEP 8 trial, which directly compared the two treatments[1,3,4]