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The hepatic extraction ratio in humans is low, suggesting that the low oral bioavailability results from the high polarity of Lcarnitine limiting passive diffusion, the limited capacity of intestinal transporters and acetylation in the intestinal epithelium

Nevi on the scalp Clinical features Nevi on the scalp occur most frequently on the occipital region, followed by left parietal region, right parietal region, and frontal region (Fig 25.69)

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