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Cardiovascular outcomes Semaglutide (SELECT) in overweight/obesity without diabetes: 20% reduction in 3-point MACE (Pfeffer et al., 2023)

Acknowledgements We thank Diana van Tuijl, Inge Wolterink-Donselaar, Jos Brits, Harrie van der Eerden, and Henk Spierenburg for their practical assistance

Key limitation: compendia support does not override Part Ds statutory exclusionsso it doesnt turn an excluded weight-loss use into a covered use

In laboratory and pre-clinical research settings, FOXO4-DRI is used as the primary peptide tool for selective senescent cell elimination a strategy known as senolysis