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The GR inhibitor 2-Acetylamino-3-[4-(2-acetylamino-2-carboxy-ethylsulfanylthiocarbonylamino)phenylthiocarbamoylsulfanyl]propionic acid (2-AAPA) was prepared in DMSO, and then further diluted in MilliQ water and filter sterilised to produce a 1 mM stock solution
The subsections that follow discuss zinc, vitamin A, and pyridoxine, which are often used to treat symptoms other than delayed cognition in DS
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