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Methods: This article is a Systematic Review that synthesizes recent multi-omics and clinical evidence on mechanisms (hormonal, immune-inflammatory, oxidative stress/ferroptosis, genetic/epigenetic, microbiome/metabolic) and appraises therapeutic strategies spanning surgery, hormonal suppression, assisted reproductive technologies (ART), and emerging adjuncts

In this study, we found both PKA inhibitors (Rp-cAMP and H-89) and PI3K inhibitors (LY294002 and wortmannin) abrogated the anti-apoptotic effect of GLP-1 in RINm5F cells based on the results of MTT assay (Fig

Healthcare digitalization and AI-driven patient engagement tools support adherence

Weight management is a complex issue influenced by genetics, hormones, metabolism, and lifestyle factors