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doi: 10.1093/nar/gkae973 Summary Keywords gut-bone axis, osteoporosis, gut microbiota, immune and endocrine regulation, orthopedic diseases, bone metabolism, bone health Citation Gu C, Du H, Li N, Zhou Y, Li S, Sun Y, Han Y, Xu X and Li X (2025) The gutbone axis in osteoporosis: a multifaceted interaction with implications for bone health