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Previous studies have demonstrated that the aqueous humor of glaucoma patients shows alterations in the levels of certain proteins, such as those that contribute to oxidative damage, mitochondrial damage, neural degeneration, apoptosis, immune responses, and the complement cascade 19,20,21,22

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These factors, as well as obesity-related leptin resistance, were shown to have somnogenic activity

As a result, patients feel fuller longer, eat less, and experience fewer cravings throughout the day