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Authors: Thomas Kruse, Jakob Lerche Hansen, Kirsten Dahl, Lauge Schffer, Ulrich Sensfuss, Christian Poulsen, Morten Schlein, Ann Maria Kruse Hansen, Claus Bekker Jeppesen, Charlotta Dornonville de la Cour, Trine Ryberg Clausen, Eva Johansson, Simone Fulle, Rikke Bjerring Skyggebjerg, Kirsten Raun URL: This paper details the medicinal chemistry efforts that led to the design and synthesis of cagrilintide, a long-acting amylin analogue for the treatment of obesity

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While Ozempic itself is not directly nephrotoxic, dehydration from GI side effects can stress kidneys that may already have reduced reserve capacity

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