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In this post hoc analysis of SURMOUNT-5, we assessed the proportion of participants achieving normoglycemia, changes in glycemic control and related estimates of insulin resistance and insulin sensitivity, and changes in body weight with tirzepatide vs semaglutide among participants with obesity and prediabetes at baseline

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Peer review Peer review information Nature Communications thanks Matteo Villa, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work