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As collagen breaks down with age, replenishment is crucial to maintaining a youthful appearance

In this study, we used hippocampal cultures, electrophysiology, live imaging, immunofluorescence and genetic transfections to fill the existing gap of information on long-term actions of BDNF on synaptic dynamics

In recent GLP-1RA trials focusing on patients with obesity, favourable effect on worsening heart failure in HFpEF patients was indicated to be modulated by baseline BMI [32], although the underlying mechanisms that explain the cardiovascular and renal benefits may not necessarily be due to weight loss alone

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