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Subjective pain reduction often reported within 24-48 hours: likely analgesic/NO effect rather than structural healing

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To formulate the PNP hydrogels, a suspension of biodegradable PEG-PLA nanoparticles containing the therapeutic peptide was mixed with a solution of dodecyl-modified hydroxypropyl methylcellulose (HPMC-C12) ( Figure 1C )

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