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We also tested the effects of semaglutide on binge-like and dependence-induced alcohol drinking in male and female rats, as well as acute effects of semaglutide on spontaneous inhibitory postsynaptic currents (sIPSCs) from central amygdala (CeA) and infralimbic cortex (ILC) neurons

GLP-1 drugs prescribed for weight loss and diabetes are currently under federal investigation

GABA Homeostasis Under Depression GABAergic system is involved in most psychiatric disorders including major depressive disorder (131), schizophrenia (132), bipolar disorder (133) and autism (134)

In November 2023, the FDA approved Zepbound for weight management in adults with obesity