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However, their in vivo efficacy is often constrained by their low bioavailability, influenced by physicochemical characteristics, intestinal absorption, hepatic metabolism, gut microbiota composition, etc

Selenium deficiency can also interfere with converting T4 to T3, further reducing thyroid hormone activity

High hepatic fat content is the important inducement of the impairment of redox imbalance and insulin resistance

Transplantation of BSO-treated skin organoids with fewer P63 + cells onto the back of nude mice led to significantly fewer hair regeneration compared to the control (Fig