L-Arginine is sometimes used as a similar supplement, however L-Citrulline is more bioavailable, easier on the digestive system, more effective and has a longer-lasting effect
Meanwhile, peptides have gained attention in recent years due to their non-toxic and effective properties, attracting significant interest from researchers 25,29,30
The Look AHEAD: Action for Health in Diabetes (Look AHEAD) trial on the longer-term effects of an intensive lifestyle intervention in adults who were overweight/obese with type 2 diabetes showed improvements in diabetes control and complications, depression, physical function and health-related quality of life, sleep apnoea, incontinence, brain structure and healthcare use and costs, with positive impacts on composite indices of multimorbidity, geriatric syndromes and disability-free life-years
It plays a role in collagen production, tissue regeneration, and overall skin health