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Using advanced tracer methodologies, the researchers identified a fascinating metabolic phenomenon they termed "brain glucose steal." Due to systemic mitochondrial impairment, non-brain organs were essentially stealing glucose intended for the central nervous system, starving the brain of energy and driving cognitive dysfunction

The increased absorption of calcium ions requires concomitant absorption of a negatively charged counter ion to maintain electrical neutrality

doi: 10.1016/j.celrep.2018.08.003 19 ColuzziE.LeoneS.SguraA

Additionally, mitochondrial dysfunction in spermmanifested as decreased mitochondrial MMPimpairs energy metabolism and reduces motility [9, 11]